Clinical performance of automated chemiluminescent methods for anticardiolipin and anti-β2-glycoprotein I antibodies detection in a large cohort of Chinese patients with antiphospholipid syndrome.

Li-Yan WanJie-Yu GuTing-Ting LiuQiong-Yi HuJin-Chao JiaJia-Lin TengYue SunHong-Lei LiuXiao-Bing ChengJun-Na YeYu-Tong SuXin-Yao WuHui-Hui ChiZhuo-Chao ZhouZhi-Hong WangJin-Feng ZhouGary L NormanJing DaiCheng-de YangHui Shi

Published in: International journal of laboratory hematology (2020)

CIA measurements had a good agreement and correlation with comparative ELISA assays. The CIA anti-β2GPI IgG however was significantly more sensitive for APS diagnosis. The two assay methodologies showed comparable predictive powers and support the value of the CIA method for improved diagnosis and management of patients with APS.

Keyphrases

high throughput
machine learning
deep learning
loop mediated isothermal amplification
label free
single cell
monoclonal antibody
quantum dots