Chronic cerebral infarctions and white matter lesions link to long-term survival after a first ischemic event: A cohort study.

Marina SchilterAlessandra EpsteinJan VynckierAdnan MujanovicNebiyat Filate BelachewMorin BeyelerBernhard SiepenMartina GoeldlinAdrian ScutelnicDavid Julian SeiffgeSimon JungJan GrallaTomas DobrockyMarcel ArnoldJohannes KaesmacherUrs FischerThomas Raphael Meinel

Published in: Journal of neuroimaging : official journal of the American Society of Neuroimaging (2022)

WMH represent a strong surrogate biomarker of long-term mortality in first-ever manifest AIS or TIA patients. CBI phenotypes, count, and location seem less relevant. Incorporation of CBI and WMH slightly improves predictive capacity of established risk scores.

Keyphrases

white matter
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
cardiovascular events
risk factors
cardiovascular disease
coronary artery disease
oxidative stress
brain injury
drug induced