Contribution of a genetic risk score to ethnic differences in fatty liver disease.

Maddie J KubiliunJonathan C CohenHelen H HobbsJulia Kozlitina

Published in: Liver international : official journal of the International Association for the Study of the Liver (2022)

Blacks had a lower and Hispanics a greater FLD risk allele burden than Whites. These differences contributed to, but did not fully explain, racial/ethnic differences in FLD prevalence. Identification of additional factors protecting Blacks from FLD may provide new targets for prevention and treatment of FLD.

Keyphrases

risk factors
genome wide
dna methylation
copy number
combination therapy