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Proteomics approach for biomarker discovery in Kawasaki disease.

Rajni KumrahAnkur Kumar JindalDeepti SuriSurjit Singh
Published in: Expert review of clinical immunology (2024)
Efforts to improve the clinical and diagnostic evaluation of KD have focused on general markers of inflammation which are not specific for KD. Identification of a proteomic based biomarker can reliably and specifically differentiate KD from other disease and would help in the prompt diagnosis. Comprehensive analysis of serum proteome of patients with KD may be helpful in identifying candidate protein biomarkers.
Keyphrases
  • oxidative stress
  • small molecule
  • mass spectrometry
  • label free
  • high throughput
  • binding protein