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OPTIMAL: Titration of anti-IL5 biologics in severe asthma - An open label randomised controlled trial.

Marianne Baastrup SoendergaardAnne-Sofie BjerrumLinda Makowska RasmussenSofie Lock-JohanssonOle HilbergSusanne HansenAnna von BulowCeleste Porsbjerg
Published in: The European respiratory journal (2024)
This study serves as a proof-of-concept for titration of anti-IL5 biologics in patients with severe asthma with clinical control on treatment, and the OPTIMAL algorithm provides a potential framework for individualising dosing intervals in the future.
Keyphrases
  • machine learning
  • study protocol
  • replacement therapy