Health outcomes and costs in patients with osteoarthritis and chronic pain treated with opioids in Spain: the OPIOIDS real-world study.
Antoni Sicras MainarCarlos Tornero-TorneroFrancisco Vargas-NegrínIsabel LizarragaJavier Rejas-GutierrezPublished in: Therapeutic advances in musculoskeletal disease (2020)
In real-world practice in Spain, opioid use in osteoarthritis was high, but with low adherence. There were meaningful increases in resource use and costs for the National Health System. Pain reduction was modest, whereas cognitive impairment and dependence for BADL increased significantly.