Effects of the sodium-glucose cotransporter 2 inhibitor dapagliflozin on fluid distribution: A comparison study with furosemide and tolvaptan.
Ken OharaTakahiro MasudaTakuya MurakamiToshimi ImaiHiromichi YoshizawaSaki NakagawaMari OkadaAtsushi MikiAkihiro MyogaTaro SugaseChuji SekiguchiYasuharu MiyazawaAkito MaeshimaTetsu AkimotoOsamu SaitoShigeaki MutoDaisuke NagataPublished in: Nephrology (Carlton, Vic.) (2019)
Sodium-glucose cotransporter 2 inhibitor DAPA predominantly decreased the ECW with a mild increase in urine volume, but the change in the ECW/total body water was smaller than that in patients treated with FR, and larger than that in patients treated with TLV, suggesting that the effects of SGLT2 inhibitors on fluid distribution may differ from those of conventional diuretics.
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