Space-Time Clustering of Childhood Leukemia: Evidence of an Association with ETV6-RUNX1 (TEL-AML1) Fusion.

Christian KreisJudith E LupatschFelix NiggliMatthias EggerClaudia E KuehniBen D Spychernull null

Published in: PloS one (2017)

Our findings suggest ETV6-RUNX1 is associated with space-time clustering of CL and are consistent with an infection interacting with that oncogene in early life leading to clinical leukemia.

Keyphrases

early life
acute myeloid leukemia
acute lymphoblastic leukemia
transcription factor
single cell
bone marrow
rna seq
allogeneic hematopoietic stem cell transplantation
young adults