Serum IGF-1 to IGFBP-3 Molar Ratio: A Promising Diagnostic Tool for Growth Hormone Deficiency in Children.

Laith M Haj-AhmadMuhannad M MahmoudNabil W G SweisIsam BsisuAhmad M AlghrabliAlaa M IbrahimAyman A Zayed

Published in: The Journal of clinical endocrinology and metabolism (2022)

Our data suggest that the serum IGF-1/IGFBP-3 ratio is a useful marker for the diagnosis of GHD in children who do not have other disorders that may affect serum IGF-1 levels. Further large studies are needed to confirm the diagnostic utility of the serum IGF-1/IGFBP-3 ratio.

Keyphrases

growth hormone
young adults
pi k akt
binding protein
machine learning
signaling pathway
cell proliferation