Deletion of Bmal1 in aggrecan-expressing cells leads to mouse temporomandibular joint osteoarthritis.
Lifan LiaoLin YangYu LiJiale HuHuang LuHuan LiuJiahao HuangLonglong HeZhaoli MengJianfei LiangDi ChenQin ZhouXiaofeng ChangShufang WuPublished in: Journal of bone and mineral metabolism (2024)
We demonstrated that Bmal1 was essential for TMJ tissue homeostasis and loss-of-function of Bmal1 in chondrocytes leads to the development of TMJ OA.