The role of high airway pressure and dynamic strain on ventilator-induced lung injury in a heterogeneous acute lung injury model.

Sumeet V JainMichaela Kollisch-SinguleJoshua SatalinQuinn SearlesLuke DombertOsama Abdel-RazekNatesh YepuriAntony LeonardAngelika GruessnerPenny AndrewsFabeha FazalQinghe MengGuirong WangLouis A GattoNader M HabashiGary F Nieman

Published in: Intensive care medicine experimental (2017)

Both NT and ALIT are resistant to VILI caused by OD alone, but when combined with a HDS, significant tissue injury develops.

Keyphrases

high glucose
lipopolysaccharide induced
diabetic rats
lps induced
acute respiratory distress syndrome
mechanical ventilation
drug induced
endothelial cells
oxidative stress