SRSF1 regulates primordial follicle formation and number determination during meiotic prophase I.

Longjie SunZheng LvXuexue ChenChaofan WangPengbo LvLu YanShuang TianXiaomei XieXiaohong YaoJingjing LiuZhao WangHaoshu LuoSheng CuiJiali Liu

Published in: BMC biology (2023)

Altogether, our data reveal the critical role of an SRSF1-mediated posttranscriptional regulatory mechanism in the mouse oocyte meiotic prophase I program, providing a framework to elucidate the molecular mechanisms of the posttranscriptional network underlying primordial follicle formation.

Keyphrases

germ cell
electronic health record
transcription factor
genome wide
big data
mass spectrometry
deep learning
artificial intelligence