Multiomics analyses identified epigenetic modulation of the S100A gene family in Kawasaki disease and their significant involvement in neutrophil transendothelial migration.

Lien-Hung HuangHo-Chang KuoCheng-Tsung PanYeong-Shin LinYing-Hsien HuangSung-Chou Li

Published in: Clinical epigenetics (2018)

This is the first study to integrate genome-wide DNA methylation with gene expression assays in KD and showed that the S100A family plays important roles in the pathogenesis of KD.

Keyphrases

dna methylation
genome wide
gene expression
copy number
high throughput
single cell