Delayed Rise of Oral Fluid Antibodies, Elevated BMI, and Absence of Early Fever Correlate With Longer Time to SARS-CoV-2 RNA Clearance in a Longitudinally Sampled Cohort of COVID-19 Outpatients.
Annukka A R AntarTong YuNora PisanicRazvan AzamfireiJeffrey A TornheimDiane M BrownKate KruczynskiJustin P HardickThelio SewellMinyoung JangTaylor ChurchSamantha N WalchCarolyn ReulandVismaya S BachuKirsten LittlefieldHan-Sol ParkRebecca L UrsinAbhinaya GanesanOyinkansola KusemijuBrittany BarnabaCurtisha CharlesMichelle PrizziJaylynn R JohnstoneChristine PaytonWeiwei DaiJoelle FuchsGuido MassaccesiDerek T ArmstrongJennifer L TownsendSara C KellerZoe O DemkoChen HuMei-Cheng WangLauren M SauerHeba H MostafaJeanne C KerulyShruti H MehtaSabra L KleinAndrea L CoxAndrew S PekoszChristopher D HeaneyDavid L ThomasPaul W BlairYukari C ManabePublished in: Open forum infectious diseases (2021)
We demonstrate that delayed rise of oral fluid SARS-CoV-2-specific antibodies, elevated BMI, and absence of early fever are independently associated with delayed URT viral RNA clearance.