Genetic determinants of circulating metabolites and the risk of stroke and its subtypes.

Rong-Ze WangShu-Yi HuangHong-Qi LiYu-Xiang YangShi-Dong ChenJin-Tai Yu

Published in: European journal of neurology (2022)

Genetically determined levels of lipids in small LDL were associated with the risk of stroke, suggesting that a therapeutic strategy targeting small LDL levels may be crucial for stroke prevention. HDL-C was positively associated with the risk of intracerebral haemorrhage.

Keyphrases

atrial fibrillation
cerebral ischemia
genome wide
gene expression
dna methylation
drug delivery
copy number
blood brain barrier
subarachnoid hemorrhage