Vaccine Targeting Alpha 1D-Adrenergic Receptor Improved Metabolic Syndrome in Mice.

Xin LiWenrui MaYanzhao ZhouChang LiDingyang ShiWenlong KuangJiacheng WuYuhua LiaoZhihua QiuZihua Zhou

Published in: Cardiovascular drugs and therapy (2023)

This study demonstrated for the first time that the ADRQβ-004 vaccine targeting α1D-AR improved obesity, hypertension, dyslipidemia, and dysglycemia, and further reduced end-organ damage, which may provide new motivation for MetS research.

Keyphrases

metabolic syndrome
high fat diet induced
insulin resistance
blood pressure
type diabetes
weight loss
oxidative stress
cardiovascular disease
cardiovascular risk factors
body mass index