Trapa Bispinosa Roxb. Inhibits the Insulin-Dependent AKT/WNK1 Pathway to Induce Autophagy in Mice with Type 2 Diabetes.
Takahiro SuzukiTakehito SatoKaori MasuharaMizuki TokusanaiHisako AkatsukaTomohiro KashikawaYasuyuki SuzukiPublished in: Diabetes, metabolic syndrome and obesity : targets and therapy (2023)
In type 2 diabetes, it was suggested that TBE inhibits the insulin-dependent AKT/WNK1 pathway to induce autophagy, and thereby might promote anti-glycation and reduce retinal damage.