Inputs to the locus coeruleus from the periaqueductal gray and rostroventral medulla shape opioid-mediated descending pain modulation.
Susan T LubejkoGiulia LivrizziJanki PatelJean C YungTony L YakshMatthew Ryan BanghartPublished in: bioRxiv : the preprint server for biology (2023)
Convergent synaptic activation of noradrenergic neurons in the locus coeruleus drives systemic opioid antinociception.