Using seconds-resolved pharmacokinetic datasets to assess pharmacokinetic models encompassing time-varying physiology.

Matthew H McDonough Sophie Lena StockerTod E KippinWendy MeiringKevin W Plaxco

Published in: British journal of clinical pharmacology (2023)

Our results highlight both the impact that simple physiological changes (such as varying kidney function) can have on drug pharmacokinetics and the ability of high-time resolution EAB sensor measurements to identify such impacts.

Keyphrases

single molecule
adverse drug
emergency department