Adjunctive posterior wall isolation for the treatment of persistent and longstanding persistent atrial fibrillation (CORNERSTONE AF) trial: Design and rationale.
Takatoshi ShigetaShinsuke MiyazakiOsamu InabaYukihiro InamuraJunichi NittaYukio SekiguchiAtsushi TakahashiHitoshi HachiyaYasutoshi NagataYasuteru YamauchiTatsuya HayashiShinsuke IwaiAkira MizukamiYuichi OnoKeita HandaMakoto SuzukiAtsushi SuzukiJun NakajimaKenzo HiraoHiroyuki OkadaMiho NegishiTakashi IkenouchiTasuku YamamotoKentaro GotoTakuro NishimuraSusumu TaoMasateru TakigawaAkihiro HirakawaMasahiko GoyaTetsuo SasanoPublished in: Clinical cardiology (2023)
The CORNERSTONE AF study is a prospective, randomized, multicenter trial designed to evaluate the efficacy and safety of an adjunctive empirical LAPWI following standard AF ablation in persistent AF patients.
Keyphrases
- atrial fibrillation
- catheter ablation
- oral anticoagulants
- left atrial
- clinical trial
- end stage renal disease
- left atrial appendage
- phase iii
- study protocol
- direct oral anticoagulants
- heart failure
- ejection fraction
- phase ii
- newly diagnosed
- percutaneous coronary intervention
- prognostic factors
- chronic kidney disease
- peritoneal dialysis
- open label
- double blind
- combination therapy
- replacement therapy