Cisplatin eligibility in the neoadjuvant setting of patients with muscle-invasive bladder cancer undergoing radical cystectomy.
Renate PichlerJosef FritzAndrea MariAnna CadenarMarkus von DeimlingGautier MarcqFrancesco Del GiudiceCostantino LeonardoEugenio BolognaKeiichiro MoriRana TahbazMaria De SantisTobias KlatteBarbara ErberFelizian LacknerAndreas KronbichlerPeter Andreas SeeberMargit FischMarco MoschiniBenjamin PradereLaura S MertensPublished in: The oncologist (2024)
Comparing calculated eGFR formulas, similar percentages of patients with MIBC were deemed cisplatin-ineligible. However, a significant number of patients could be upgraded by being cisplatin-fit based on measured CrCI, particularly when the calculated eGFR was falling within the gray range of 40-59 mL/minute.