How Communicating Polygenic and Clinical Risk for Atherosclerotic Cardiovascular Disease Impacts Health Behavior: an Observational Follow-up Study.
Elisabeth WidénNella JunnaSanni RuotsalainenIda SurakkaNina J MarsPietari RipattiJuulia J PartanenJohanna AroPekka MustonenTiinamaija TuomiAarno PalotieVeikko V SalomaaJaakko A KaprioJukka PartanenKristina HotakainenPasi PöllänenSamuli RipattiPublished in: Circulation. Genomic and precision medicine (2022)
Web-based communication of personal atherosclerotic cardiovascular disease risk-data including polygenic risk to middle-aged persons motivates positive changes in health behavior and the propensity to seek care. It supports integration of genomic information into clinical risk calculators as a feasible approach to enhance disease prevention.