The Plasma Lipidomic Landscape in Patients with Sepsis due to Community-acquired Pneumonia.
Osoul ChouchaneAlex R SchuurmanTom D Y ReijndersHessel Peters SengersJoe M ButlerFabrice UhelMarcus J SchultzMarc J BontenOlaf L CremerCarolyn S CalfeeMichael A MatthayRaymond J LangleyNarges Alipanah-LechnerStephen F KingsmoreAngela RogersMichel van WeeghelFrédéric M VazTom van der PollPublished in: American journal of respiratory and critical care medicine (2024)
Patients with sepsis due to CAP display a time-dependent and partially disease-specific shift in their plasma lipidome that correlates with disease severity and systemic inflammation, and is associated with higher mortality.