Evaluation of serum levels of Irisin as a marker of endothelial dysfunction in patients with type 2 diabetes mellitus.
Thoraya Mohamed AhmedMahmoud NassarHanaa Ahmed Abdallah MohamedKhaled El-Sayed ElhadidyHanan Mohamed FarhanAhmed Sayed Abd El BassetRiem M ElmessieryMahmoud Farid KamelPublished in: Endocrinology, diabetes & metabolism (2023)
In patients with T2DM, serum levels of irisin were inversely correlated with hyperglycaemia, body mass index and per cent body fat; this suggests that detecting irisin levels early can prevent cardiovascular diseases from progressing. According to the study results, serum irisin serves as a predictive marker for early cardiovascular disease, thus preventing the disease from progressing. There is a need for further research in order to understand how irisin contributes to the development of atherosclerosis and the development of diabetic complications.