Long term outcomes of initial infliximab therapy for inflammatory pouch pathology: a multi-Centre retrospective study.
Jonathan P SegalLawrence PenezSoad Mohsen ElkadyGuy H T WorleySimon D McLaughlinBenjamin Harvey MullishMohammed N QuraishiNik Sheng DingTamara GlynKesavan KandiahMark A SamaanPeter M IrvingOmar D FaizSusan K ClarkAilsa L HartPublished in: Scandinavian journal of gastroenterology (2018)
Initial IFX therapy for pouch inflammatory conditions is associated with IFX failure in just over half of all patients. Despite a high failure rate, an ileostomy can be avoided in almost three-quarters of patients at four years by using other medical therapies.