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Post-Authorization Safety Studies of Acute Liver Injury and Severe Complications of Urinary Tract Infection in Patients with Type 2 Diabetes Exposed to Dapagliflozin in a Real-World Setting.

Heather E DanyshCatherine B JohannesDaniel C BeachlerJ Bradley LaytonRyan ZiemieckiAlejandro AranaJade DinhLing LiBrian CalingaertManel PladevallPhillip R HuntHungta ChenCecilia KarlssonKristina JohnssonAlicia W Gilsenan
Published in: Drug safety (2022)
These real-world studies do not suggest increased risks of hALI or sUTI, and they suggest a potential decreased risk of sUTI with dapagliflozin exposure compared with other GLDs.
Keyphrases
  • drug induced
  • liver injury
  • urinary tract infection
  • case control
  • human health
  • liver failure
  • risk factors
  • early onset
  • risk assessment
  • intensive care unit
  • climate change