Cannabis smoke suppresses antiviral immune responses to influenza A in mice.

Nadia MiladMatthew F FantauzziJoshua J C McGrath Steven P CassDanya ThayaparanPeiyao WangSam AfkhamiJennifer A AguiarKjetil Ask Andrew Charles DoxeyMartin R StampfliJeremy A Hirota

Published in: ERJ open research (2023)

Overall, cannabis smoke exposure disrupted host-defence processes, leading to increased viral burden and dampened inflammatory signalling. These results suggest that cannabis smoking is detrimental to the maintenance of pulmonary homeostasis during viral infection and highlight the need for data regarding the impact on immune competency in humans.

Keyphrases

immune response
sars cov
pulmonary hypertension
oxidative stress
signaling pathway
high fat diet induced
big data
dendritic cells
risk factors
machine learning
metabolic syndrome
inflammatory response
resting state
functional connectivity
insulin resistance