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IL4Rα and IL13Rα1 Are Involved in the Development of Human Gallbladder Cancer.

Sung-Woo AhnChang Min LeeMi-Ae KangUsama Khamis HusseinHo Sung ParkAe-Ri AhnHee Chul YuJae Do YangYung-Hun YangKyungmoon ParkChang Seok LeeKyu Yun JangSee-Hyoung Park
Published in: Journal of personalized medicine (2022)
Taken together, our results suggest that IL4Rα and IL13Rα1 might be involved in the development of human gallbladder cancer cells and IL4Rα and IL13Rα1 complex/JAK2 signaling pathway could be efficient therapeutic targets for gallbladder cancer treatment.
Keyphrases
  • endothelial cells
  • signaling pathway
  • epithelial mesenchymal transition
  • oxidative stress
  • cell proliferation
  • lymph node metastasis