Hepatic exosomes with declined MiR-27b-3p trigger RIG-I/TBK1 signal pathway in macrophages.
Jie YouWenyu WuMengxin LuYanghao XieRui MiaoMisi GuDong XiWeiming YanDi WuXiaojing WangTao ChenQin NingMeifang HanPublished in: Liver international : official journal of the International Association for the Study of the Liver (2022)
In IFNα treatment, exosomes with declined miR-27b-3p triggered activation of RIG-I/TBK1 signalling in macrophages against HBV. Serum exosomal miR-27-3p might represent a potential biomarker for patients with CHB.