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Defining functional diversity for lignocellulose degradation in a microbial community using multi-omics studies.

Anna M AlessiSusannah M BirdNicola C OatesYi LiAdam A DowleEtelvino H NovotnyEduardo R deAzevedoJoseph P BennettIgor PolikarpovJ Peter W YoungSimon J McQueen-MasonNeil C Bruce
Published in: Biotechnology for biofuels (2018)
A combination of mass spectrometry-based proteomics coupled with metatranscriptomics has enabled the identification of a large number of lignocellulose degrading enzymes that can now be further explored for the development of improved enzyme cocktails for the treatment of plant-based feedstocks. In addition to the expected carbohydrate-active enzymes, our studies reveal a large number of unknown proteins, some of which may play a crucial role in community-based lignocellulose degradation.
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