Long-term auditory follow-up in the management of pediatric platinum-induced ototoxicity.

Anna Rita Fetoni Francesca Brigato Eugenio De Corso Daniela Lucidi Bruno Sergi Emanuele Scarano Jacopo Galli Antonio Ruggiero

Published in: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery (2022)

Long-term monitoring of at least 5 years prevents the harmful effects of hearing deprivation identifying late onset/progressive hearing loss after platinum compound chemotherapy in children thanks to early hearing rehabilitation, especially in those who underwent multimodal therapy or subjected to irradiation.

Keyphrases

hearing loss
late onset
early onset
multiple sclerosis
young adults
high glucose
diabetic rats
working memory
stem cells
squamous cell carcinoma
drug induced
endothelial cells
mesenchymal stem cells
chronic pain
childhood cancer
stress induced