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The prognostic value of high-grade prostate cancer pattern on MRI-targeted biopsies: predictors for downgrading and importance of concomitant systematic biopsies.

Cécile ManceauGaëlle Fromont-HankardJean-Baptiste BeauvalMarine LesourdChristophe AlmerasAnne-Sophie BajeotJean-Romain GautierMichel SouliéGuillaume LoisonAmbroise SalinChristophe TollonBernard MalavaudMathieu RoumiguiéGuillaume Ploussard
Published in: World journal of urology (2021)
Our data shows that a limited HG restricted to TB can often be associated with a favorable grade in almost a quarter of the cases and downgraded in almost half of the cases. Detailed SB features, mainly the presence of HG on concomitant SB, was associated with a more accurate pathology and oncologic outcomes prediction, pleading for the maintenance of SB in MRI-positive patients.
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