Prognostic factors for head and neck cancer of unknown primary including the impact of human papilloma virus infection.

Lars AxelssonJan NymanHedda Haugen-CangeMogens BoveLeif JohanssonShahin De LaraAnikó KovácsEva Hammerlid

Published in: Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale (2017)

Curatively treated HNCUP had good survival. HPV infection was common. Independent prognostic factors for survival were age over 70 years, HPV status and N3 stage. We recommend that HPV analysis should be performed routinely for HNCUP. Treatment with neck dissection and postoperative radiation or (chemo) radiation showed similar survival rates.

Keyphrases

prognostic factors
high grade
free survival
endothelial cells
patients undergoing
photodynamic therapy
cervical cancer screening
radiation induced
cancer therapy
drug delivery
newly diagnosed