Bimetallic nanozymes synergize to regulate the behavior of oxygen intermediates and substrate HMF adsorption.

We have constructed a bimetallic (CoNiP) nanozyme, leveraging the synergistic effect of cobalt and nickel, which efficiently catalyzes the oxidation of TMB from colorless to ox-TMB (blue). Density functional theory (DFT) calculations further highlight the pivotal role of this synergistic effect in improving the adsorption energy of oxygen intermediates, accelerating the catalytic process.