Natural mineral fibers: conducting inhalation toxicology studies-part B: development of a nose-only exposure system for repeat-exposure in vivo study of Libby amphibole aerosol.
Anbo WangAmit GuptaMichael D GrimmDavid T PressburgerBarney R SparrowJamie S RicheyJohn R ShawKaren E ElsassGeorgia K RobertsPei-Li YaoMatthew D StoutBenjamin J EllisRobyn L RayPublished in: Inhalation toxicology (2023)
The exposure system developed is ready for use in conducting nose-only inhalation toxicity studies of LA 2007 in rats. The exposure system is anticipated to have applicability for the inhalation toxicity evaluation of other natural mineral fibers of concern.
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