Tapering of biological treatment in autoinflammatory diseases: a scoping review.

Tatjana WelzelLea OefeleinMarinka TwiltMarc PfisterJasmin B Kuemmerle-DeschnerSusanne M Benseler

Published in: Pediatric rheumatology online journal (2022)

Tapering of biological treatment after sustained inactive disease should be considered. Guidance for optimal strategies is limited. Future studies may leverage therapeutic drug monitoring in combination with pharmacometric modelling to further enhance personalized "taper-to-target" strategies respecting individual patients and diseases aspects.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
prognostic factors
combination therapy
peritoneal dialysis
current status
patient reported outcomes
patient reported