Serum Th-2 cytokines and FEV1 decline in WTC-exposed firefighters: A 19-year longitudinal study.
Michael D WeidenAnkura SinghDavid G GoldfarbBarbara PutmanRachel A Zeig-OwensTheresa SchwartzHillel W CohenDavid J PrezantPublished in: American journal of industrial medicine (2021)
In WTC-exposed firefighters with accelerated-FEV1 -decline, elevated serum IL-4 measured both 1-6 months and 12-13 years after 9/11 is associated with greater FEV1 decline/year. Drugs targeting the IL-4 pathway may improve lung function in this high-risk subgroup.