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Bone regeneration in Ds-Red pig calvarial defect using allogenic transplantation of EGFP-pMSCs - A comparison of host cells and seeding cells in the scaffold.

Ming-Kai HsiehChia-Jung WuXuan-Chun SuYi-Chen ChenTsung-Ting TsaiChi-Chien NiuPo-Liang LaiShinn-Chih Wu
Published in: PloS one (2019)
Our in vivo results showed that more seeded cells recruit more host cells and that both cell types participate in osteogenesis. These results suggest that scaffolds without seeded cells may not be effective in bone transplantation.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • bone regeneration
  • signaling pathway
  • mesenchymal stem cells
  • cell therapy
  • cell proliferation
  • bone mineral density
  • tissue engineering