Left Atrial Appendage Closure Compared With Oral Anticoagulants for Patients With Atrial Fibrillation: A Systematic Review and Network Meta-Analysis.

Angelo Oliva Anna Maria IoppoloMauro ChiaritoAlberto CremonesiAlessia AzzanoEligio Miccichè Andrea Mangiameli Francesco Ariano Giuseppe Ferrante Bernhard Reimers Philippe Garot Nicolas Amabile Roxana Mehran Gianluigi Condorelli Giulio Giuseppe Stefanini Davide Cao

Published in: Journal of the American Heart Association (2024)

As a nonpharmacological alternative to oral anticoagulation for atrial fibrillation, LAAC showed similar efficacy and safety compared with VKAs or DOACs. Prospective confirmation from larger studies is warranted.

Keyphrases

atrial fibrillation
left atrial appendage
oral anticoagulants
direct oral anticoagulants
catheter ablation
left atrial
case control
heart failure
percutaneous coronary intervention
acute coronary syndrome