The genomic landscape of Cronkhite-Canada syndrome: Possible clues for pathogenesis.
Shuang LiuRun Feng ZhangYan YouWen YouGe Chong RuanYa Ping LiuSheng Yu ZhangYue LiYun Lu FengXue Min YanWei Xun ZhouJing Nan LiJi LiJia Ming QianPublished in: Journal of digestive diseases (2022)
CCS has genomic alteration patterns completely distinct from those of traditional hamartomatous polyposis syndrome. The germline mutation landscape indicates potential roles of innate immune responses and glycosylation in the pathogenesis of CCS.