Brusatol attenuated proliferation and invasion induced by KRAS in differentiated thyroid cancer through inhibiting Nrf2.
Z GongL XueA C VlantisC A van HasseltJ Y K ChanJ FangR WangY YangD LiX ZengM C F TongGeorge Gong ChenPublished in: Journal of endocrinological investigation (2023)
Collectively, this study suggests that Nrf2 could be a promising therapeutic target in KRAS-mediated dedifferentiation of thyroid cancer.