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Brusatol attenuated proliferation and invasion induced by KRAS in differentiated thyroid cancer through inhibiting Nrf2.

Z GongL XueA C VlantisC A van HasseltJ Y K ChanJ FangR WangY YangD LiX ZengM C F TongGeorge Gong Chen
Published in: Journal of endocrinological investigation (2023)
Collectively, this study suggests that Nrf2 could be a promising therapeutic target in KRAS-mediated dedifferentiation of thyroid cancer.
Keyphrases
  • oxidative stress
  • wild type
  • signaling pathway