TRAF3 suppression encourages B cell recruitment and prolongs survival of microbiome-intact mice with ovarian cancer.
Jonathan ZoreaYair MotroRoei D MazorYifat Koren CarmiZiv ShulmanJamal MahajnaJacob Moran-GiladMoshe ElkabetsPublished in: Journal of experimental & clinical cancer research : CR (2023)
TRAF3 is a tumor-derived immune-suppressive modulator that influences B-cell infiltration and activation, making it a potential target for enhancing anti-tumor B-cell responses in OC.