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The inhibitory effects of capillarisin on cell proliferation and invasion of prostate carcinoma cells.

Ke-Hung TsuiYing-Ling ChangPei-Shan YangChen-Pang HouYu-Hsiang LinBing-Wei LinTsui-Hsia FengHorng-Heng Juang
Published in: Cell proliferation (2017)
Our data indicate that Cap blocked cell growth by modulation of p21, p27 and cyclins. The inhibitory effects of Cap on survivin, MMP-2, MMP-9 and STAT3 activation may account for the suppression of invasion in prostate carcinoma cells. Our data suggest that Cap might be a therapeutic agent in treating advanced prostate cancer with constitutive STAT3 or IL-6-inducible STAT3 activation.
Keyphrases
  • prostate cancer
  • cell migration
  • radical prostatectomy
  • cell proliferation
  • electronic health record
  • big data
  • benign prostatic hyperplasia
  • cell therapy
  • data analysis
  • deep learning