Prenatal diagnosis of fetuses with absent/hypoplastic nasal bone in second-trimester using chromosomal microarray analysis.

Xinying ChenYuying JiangShuhong ZengJianlong ZhuangNa Lin

Published in: Birth defects research (2024)

The present study enhances the utility of CMA in diagnosing the etiology of absent or hypoplastic nasal bone in fetuses. Further, isolated cases of absent or hypoplastic nasal bone strongly suggest the presence of chromosomal abnormalities, necessitating genetic evaluation through CMA.

Keyphrases

bone mineral density
gestational age
chronic rhinosinusitis
copy number
soft tissue
bone loss
bone regeneration
postmenopausal women
preterm birth
genome wide
body composition