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Influence of age on the pharmacokinetics, pharmacodynamics, efficacy, and safety of rivaroxaban.

Kenneth Todd MoorePeggy WongLiping ZhangGuohua PanJoAnne Foody
Published in: Current medical research and opinion (2018)
A favorable clinical profile with rivaroxaban was observed across age sub-groups, supporting the premise that dosing in older adults does not necessitate adjustment. However, it is prudent that a cautious and individualized approach is taken for treatment with any anticoagulant in older adults.
Keyphrases
  • venous thromboembolism
  • atrial fibrillation
  • physical activity
  • pulmonary embolism
  • combination therapy
  • replacement therapy
  • smoking cessation