Potential value of urinary amatoxin quantification in patients with hepatotoxic mushroom poisoning.

Ona EscodaEnric ReverterJordi To-FiguerasGregori CasalsJavier FernándezSantiago Nogué

Published in: Liver international : official journal of the International Association for the Study of the Liver (2019)

In patients with hepatotoxic mushroom poisoning, a negative urinary amatoxin quantification within 72h of intake ruled out the risk of hepatotoxicity in 92% of patients, whereas positive urinary amatoxins were associated with hepatotoxicity and severe ALI. Concentrations >55 ng/ml and ≥ 70 ng/ml were predictive of hepatotoxicity and severe ALI, respectively.

Keyphrases

drug induced
end stage renal disease
ejection fraction
newly diagnosed
early onset
chronic kidney disease
peritoneal dialysis
prognostic factors
body mass index