Microbiological Profiles of Dental Implants in Metabolic Syndrome Patients: A Case-Control Study.
Bianca Di MurroMarta MorettiEnrico De SmaeleClaudio LetiziaCarla LubranoPier Carmine PassarelliAntonio D'AddonaGiorgio PompaPiero PapiPublished in: Antibiotics (Basel, Switzerland) (2021)
There is a lack of knowledge on the possible influence of systemic conditions on peri-implantitis. The aim of this case-control study is to evaluate the difference in terms of oral pathogens' concentrations in the peri-implant sulcus of a group of patients affected by metabolic syndrome (Mets) compared to healthy subjects. For each patient, peri-implant sulcular biofilm samples were obtained by inserting two sterile endodontic paper points in the deepest aspect of the peri-implant sulcus for 30 s. The quantitative real-time polymerase chain reaction was performed to evaluate total bacterial counts of six pathogens. Patients were screened for peri-implant diseases and clinical and radiographic parameters were recorded. A total of 50 patients was enrolled in the study, 25 affected by Mets and 25 healthy. Significantly higher bacterial counts were discovered for Aggregatibacter actinomycetemcomitans (p = 0.0008), Prevotella intermedia (p = 0.0477) and Staphylococcus aureus (p = 0.034) in MetS patients compared to healthy subjects. Performing a sub-group analysis, considering peri-implant status and dividing patients by MetS diagnosis, no statistically significant (p < 0.05) differences were found. For the first time, a correlation between MetS presence and a greater prevalence of some bacterial species in the peri-implant sulcus was reported, irrespectively from peri-implant status (health vs. disease).
Keyphrases
- end stage renal disease
- ejection fraction
- metabolic syndrome
- staphylococcus aureus
- chronic kidney disease
- newly diagnosed
- prognostic factors
- peritoneal dialysis
- healthcare
- risk factors
- high resolution
- skeletal muscle
- escherichia coli
- type diabetes
- case report
- insulin resistance
- mental health
- adipose tissue
- risk assessment
- climate change
- mass spectrometry
- uric acid
- antimicrobial resistance