CD44v3 is a marker of invasive cancer stem cells driving metastasis in gastric carcinoma.

Julie GiraudLornella SeeneevassenBenoit RousseauDamien BouriezElodie SifréAlban GieseTra Ly NguyenCamille TiffonYannick LippiLamia Azzi-MartinJulie PannequinArmelle MénardEmilie BessèdeCathy StaedelFrancis MégraudGeneviève BelleannéePhilippe LehoursCaroline GronnierPierre DubusChristine Varon

Published in: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (2022)

CD44v3 is a marker of a subpopulation of CSCs with metastatic properties in GC. The identification of metastasis-initiating cells in GC represents a major advance for further development of anti-metastatic therapeutic strategies.

Keyphrases

cancer stem cells
squamous cell carcinoma
small cell lung cancer
induced apoptosis
cell cycle arrest
nk cells
gas chromatography
endoplasmic reticulum stress
cell death
bioinformatics analysis