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The role of cytokine receptor-like factor 1 (CRLF1) in facet joint osteoarthritis pathogenesis.

Pengfei XueHuricha JinXiaogang ZhouZhiming CuiDaoran Cui
Published in: Experimental gerontology (2024)
These results suggest that CRLF1 enhances chondrocytes apoptosis and extracellular matrix degration in FJOA and thus may therefore be a potential therapeutic target for FJOA.
Keyphrases
  • extracellular matrix
  • oxidative stress
  • endoplasmic reticulum stress
  • cell cycle arrest
  • rheumatoid arthritis
  • cell death
  • knee osteoarthritis
  • binding protein
  • signaling pathway
  • pi k akt