Endothelial Dysfunction Under the Scope of Arterial Hypertension, Coronary Heart Disease, and Diabetes Mellitus Using the Angioscan.
Basheer Abdullah MarzoogPublished in: Cardiovascular & hematological agents in medicinal chemistry (2023)
In conclusion, the study of endothelial function using non-invasive angioscan reflects the influence of risk factors on the vascular wall. The most severe endothelial dysfunction is expressed in patients with diabetes. The results of endothelium-dependent vasodilation and the vascular wall stiffness index (SI) correspond to the scale of evaluation of the 10-year CVD mortality risk (SCORE). These results indicate a deterioration in the vascular ability to vasodilate in patients in response to mechanical deformation of the endothelium and the effect of NO on smooth muscle vascular cells.
Keyphrases
- smooth muscle
- risk factors
- arterial hypertension
- nitric oxide
- end stage renal disease
- ejection fraction
- newly diagnosed
- induced apoptosis
- chronic kidney disease
- cardiovascular events
- type diabetes
- cardiovascular disease
- early onset
- prognostic factors
- oxidative stress
- patient reported outcomes
- insulin resistance
- drug induced